There is a review of the Fractal Design Define R4 mid-tower case posted at ocaholic today for those of you interested. Here's a quote from the review:
Almost exactly two years ago the Swedish company Fractal Design presented with the Define R3 their first midi tower. Now they launched the Define R4 which should be the next step in evolution of their Define series cases. Therefore Fractal Design should have increased the build quality and should have also added features like USB3.0.